Irish Wedding News
13/09/2013
The team of researchers, led by the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust (UHCW), have published a report that could prove vital in helping women who suffer from recurrent miscarriage.
The recurrent loss of pregnancy through miscarriage causes significant distress to couples, which is often exacerbated due to so few treatments available to clinicians.
The search for an effective treatment has previously centred on the role of natural killer cells (NK cells), and the ability of steroids to prevent miscarriage. However, scientists have been unsure about how the NK cells could contribute to a miscarriage, and therefore has raised doubts over its importance in causing pregnancy loss.
The new study, which was led by Professor Jan Brosens of Warwick Medical School, found that elevated uterine NK cells in the lining of the womb indicated a deficient production of steroids.
In turn, this deficiency leads to reduced formation of fats and vitamins that are vital for pregnancy nutrition.
Published in The Journal of Clinical Endocrinology & Metabolism, the study is the first of its kind to provide an explanation for why high levels of NK cells can cause miscarriage.
Siobhan Quenby, Professor of Obstetrics at Warwick Medical School, explained: "This work is really exciting because after years of controversy and doubt we have a crucial breakthrough. This means, quite simply, that we have excellent scientific justification for steroid based treatment to prevent miscarriage."
(JP/CD)
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Recurrent Miscarriage Study 'Could Prove Vital'
A new study could bring hope to women suffering from a recurrent miscarriage.The team of researchers, led by the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust (UHCW), have published a report that could prove vital in helping women who suffer from recurrent miscarriage.
The recurrent loss of pregnancy through miscarriage causes significant distress to couples, which is often exacerbated due to so few treatments available to clinicians.
The search for an effective treatment has previously centred on the role of natural killer cells (NK cells), and the ability of steroids to prevent miscarriage. However, scientists have been unsure about how the NK cells could contribute to a miscarriage, and therefore has raised doubts over its importance in causing pregnancy loss.
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The new study, which was led by Professor Jan Brosens of Warwick Medical School, found that elevated uterine NK cells in the lining of the womb indicated a deficient production of steroids.
In turn, this deficiency leads to reduced formation of fats and vitamins that are vital for pregnancy nutrition.
Published in The Journal of Clinical Endocrinology & Metabolism, the study is the first of its kind to provide an explanation for why high levels of NK cells can cause miscarriage.
Siobhan Quenby, Professor of Obstetrics at Warwick Medical School, explained: "This work is really exciting because after years of controversy and doubt we have a crucial breakthrough. This means, quite simply, that we have excellent scientific justification for steroid based treatment to prevent miscarriage."
(JP/CD)
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